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VR23

Product Specifications

CAS Number

1624602-30-7

Target

Proteasome, Apoptosis, Caspase

Related Pathways

Apoptosis, Ubiquitination, Proteases/Proteasome

Purity

0.9962

Bioactivity

VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.

Smiles

[O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12

Molecular Formula

C19H16ClN5O6S

Molecular Weight

477.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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