Diprotin A (TFA)
Diprotin A TFA (Ile-Pro-Ile TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) [1].
Product Specifications
CAS Number
209248-71-5
Product Name Alternative
Ile-Pro-Ile (TFA)
UNSPSC
12352209
Target
Dipeptidyl Peptidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Diprotin_A_TFA.html
Concentration
10mM
Purity
99.62
Solubility
H2O : ≥ 77.5 mg/mL
Smiles
CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1N(C([C@H]([C@@H](C)CC)N)=O)CCC1)=O.OC(C(F)(F)F)=O
Molecular Formula
C19H32F3N3O6
Molecular Weight
455.47
References & Citations
[1]Lee CS, et al. Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation. Sci Rep. 2016 Jul 6;6:29393.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
DPP-4
Citation 01
Cell Rep. 2025 Jan 25;44 (2) :115241.|Pharm Res. 2025 Jun;42 (6) :935-945.|Nature. 2025 Jul;643 (8070) :192-200.
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