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UNC2025

Product Specifications

CAS Number

1429881-91-3

Target

FLT, TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9974

Bioactivity

UNC2025 (mrx-6313) (IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.

Smiles

CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1

Molecular Formula

C28H40N6O

Molecular Weight

476.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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