Alisol B 23-acetate
Product Specifications
CAS Number
26575-95-1
Target
MMP, FXR, Apoptosis, PARP, ROS, Others, Syk, CDK
Related Pathways
Proteases/Proteasome, Angiogenesis, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, Metabolism, Others, Apoptosis, Immunology/Inflammation
Purity
0.9995
Bioactivity
1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation.
Smiles
C[C@H](C[C@H](OC(C)=O)[C@H]1OC1(C)C)C1=C2C[C@H](O)[C@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]3(C)[C@@]2(C)CC1
Molecular Formula
C32H50O5
Molecular Weight
514.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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