Shogaol
Product Specifications
CAS Number
555-66-8
Target
Autophagy|||Lipoxygenase
Related Pathways
Metabolism|||Autophagy
Purity
0.9993
Bioactivity
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS) . 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-?B and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.
Smiles
CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
Molecular Formula
C17H24O3
Molecular Weight
276.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/CF175BD2-9DAC-48D2-BAC7-D2D8637BFDFF/T6S1699
Available Sizes
Curated Selection
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