Monotropein
Product Specifications
CAS Number
5945-50-6
Target
ROS, Interleukin, Nrf2, Others, NF-κB, Apoptosis
Related Pathways
Immunology/Inflammation, Apoptosis, Others, NF-κB
Purity
0.9966
Bioactivity
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.
Smiles
[H][C@]12C=C[C@](O)(CO)[C@@]1([H])[C@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)OC=C2C(O)=O
Molecular Formula
C16H22O11
Molecular Weight
390.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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