What is the catalog number for Flavokawain B?

The catalog number for Flavokawain B is T6S0735.

What sizes are available for Flavokawain B?

Flavokawain B is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does Flavokawain B come in?

Flavokawain B is available in 7 different pack sizes.

Is Flavokawain B in stock?

Flavokawain B is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Flavokawain B?

Flavokawain B is manufactured by Molfinity.

What is the estimated delivery time for Flavokawain B?

Estimated delivery time for Flavokawain B is approximately 10 business day(s), depending on your location.

Flavokawain B

Product Specifications

CAS Number

1775-97-9

Target

ROS, PI3K, Bcl-2 Family, Caspase, NF-κB, Akt, p38 MAPK, PARP, Apoptosis, MMP

Related Pathways

Chromatin/Epigenetic, Cytoskeletal Signaling, NF-κB, MAPK, DNA Damage/DNA Repair, Immunology/Inflammation, PI3K/Akt/mTOR signaling, Apoptosis, Proteases/Proteasome

Purity

>99.99%

Bioactivity

1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.