Farrerol
Product Specifications
CAS Number
24211-30-1
Target
Akt, p38 MAPK, ERK
Related Pathways
PI3K/Akt/mTOR signaling, MAPK, Cytoskeletal Signaling
Purity
0.9996
Bioactivity
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that Farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases.
Smiles
Cc1c(O)c(C)c2OC(CC(=O)c2c1O)c1ccc(O)cc1
Molecular Formula
C17H16O5
Molecular Weight
300.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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