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Farrerol

Product Specifications

CAS Number

24211-30-1

Target

Akt, p38 MAPK, ERK

Related Pathways

PI3K/Akt/mTOR signaling, MAPK, Cytoskeletal Signaling

Purity

0.9996

Bioactivity

1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that Farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases.

Smiles

Cc1c(O)c(C)c2OC(CC(=O)c2c1O)c1ccc(O)cc1

Molecular Formula

C17H16O5

Molecular Weight

300.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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