Ro 5126766
Product Specifications
CAS Number
946128-88-7
Target
Raf, MEK
Related Pathways
MAPK
Purity
0.9881
Bioactivity
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
Smiles
CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
Molecular Formula
C21H18FN5O5S
Molecular Weight
471.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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