Ro 5126766

Product Specifications

CAS Number

946128-88-7

Target

Raf|||MEK

Related Pathways

MAPK

Purity

0.9881

Bioactivity

RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.

Smiles

CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F

Molecular Formula

C21H18FN5O5S

Molecular Weight

471.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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