PX-478
Product Specifications
CAS Number
685898-44-6
Target
HIF, Autophagy, HIF/HIF Prolyl-Hydroxylase
Related Pathways
Angiogenesis, Autophagy, Chromatin/Epigenetic, Metabolism
Purity
0.9979
Bioactivity
PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic β-cell function in diabetes mellitus and is used in type 2 diabetes mellitus research.
Smiles
Cl.Cl.N[C@@H](Cc1ccc(cc1)[N+]([O-])(CCCl)CCCl)C(O)=O
Molecular Formula
C13H20Cl4N2O3
Molecular Weight
394.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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