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PX-478

Product Specifications

CAS Number

685898-44-6

Target

HIF, Autophagy, HIF/HIF Prolyl-Hydroxylase

Related Pathways

Angiogenesis, Autophagy, Chromatin/Epigenetic, Metabolism

Purity

0.9979

Bioactivity

PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic β-cell function in diabetes mellitus and is used in type 2 diabetes mellitus research.

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Cl.Cl.N[C@@H](Cc1ccc(cc1)[N+]([O-])(CCCl)CCCl)C(O)=O

Molecular Formula

C13H20Cl4N2O3

Molecular Weight

394.12

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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