Picropodophyllin
Product Specifications
CAS Number
477-47-4
Target
Apoptosis, IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9983
Bioactivity
Picropodophyllin (Picropodophyllin (PPP) ) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM) . Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT) .
Smiles
[H][C@]12COC(=O)[C@@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1[C@@H]2O
Molecular Formula
C22H22O8
Molecular Weight
414.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![ZNF394 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A8]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
TA808931BM 100 µL
ZNF394 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A8]
Sign In for Pricing
View Details 
249461-HRP 100 µL
NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1, TLL, TLX, XTLL) (HRP)
Sign In for Pricing
View Details MBS6238294-01 0.1 mL
FOXL1 (Forkhead Box L1, FKH6, FKHL11, FREAC7) (MaxLight 750)
Sign In for Pricing
View Details MBS6238294-02 5x 0.1 mL
FOXL1 (Forkhead Box L1, FKH6, FKHL11, FREAC7) (MaxLight 750)
Sign In for Pricing
View Details