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PI-1840

Product Specifications

CAS Number

1401223-22-0

Target

Autophagy, Apoptosis, PARP, Caspase, NF-κB, Bcl-2 Family, Proteasome

Related Pathways

NF-κB, Proteases/Proteasome, Autophagy, DNA Damage/DNA Repair, Apoptosis, Ubiquitination, Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

PI-1840 (IC50 = 27 nM) is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L) .

Smiles

CCCc1ccc(OCC(=O)N(Cc2nc(no2)-c2cccnc2)C(C)C)cc1

Molecular Formula

C22H26N4O3

Molecular Weight

394.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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