PF-4989216
Product Specifications
CAS Number
1276553-09-3
Target
PI3K, Apoptosis
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis
Purity
0.9985
Bioactivity
PF-4989216 is a potent and selective PI3K inhibitor with IC50 values of 2 nM (p110α), 142 nM (p110β), 65 nM (p110γ), 1 nM (p110δ), and 110 nM (VPS34) .
Smiles
Fc1cc(ccc1-c1c(sc(N2CCOCC2)c1C#N)-c1ncn[nH]1)C#N
Molecular Formula
C18H13FN6OS
Molecular Weight
380.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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