PD168393
Product Specifications
CAS Number
194423-15-9
Target
PKC, PDGFR, Apoptosis, FGFR, EGFR, Autophagy, IGF-1R
Related Pathways
Apoptosis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Autophagy, Angiogenesis, Chromatin/Epigenetic
Purity
0.9983
Bioactivity
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
Smiles
Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1
Molecular Formula
C17H13BrN4O
Molecular Weight
369.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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