PD168393
Product Specifications
CAS Number
194423-15-9
Target
PKC|||PDGFR|||Apoptosis|||FGFR|||EGFR|||Autophagy|||IGF-1R
Related Pathways
Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic
Purity
0.9983
Bioactivity
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
Smiles
Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1
Molecular Formula
C17H13BrN4O
Molecular Weight
369.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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Tissue, Section, Matched Pairs, Human Primary and Matched Metastasis Tumor (Frozen Section Matched Pairs, Human Primary and Matched Metastasis Tumor, Breast
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