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PD168393

Product Specifications

CAS Number

194423-15-9

Target

PKC|||PDGFR|||Apoptosis|||FGFR|||EGFR|||Autophagy|||IGF-1R

Related Pathways

Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic

Purity

0.9983

Bioactivity

PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.

Smiles

Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1

Molecular Formula

C17H13BrN4O

Molecular Weight

369.22

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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