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Pamapimod

Product Specifications

CAS Number

449811-01-2

Target

Autophagy, p38 MAPK

Related Pathways

MAPK, Autophagy

Purity

0.9999

Bioactivity

Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.

Smiles

Cn1c2nc(NC(CCO)CCO)ncc2cc(Oc2ccc(F)cc2F)c1=O

Molecular Formula

C19H20F2N4O4

Molecular Weight

406.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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