Pamapimod
Product Specifications
CAS Number
449811-01-2
Target
Autophagy, p38 MAPK
Related Pathways
MAPK, Autophagy
Purity
0.9999
Bioactivity
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.
Smiles
Cn1c2nc(NC(CCO)CCO)ncc2cc(Oc2ccc(F)cc2F)c1=O
Molecular Formula
C19H20F2N4O4
Molecular Weight
406.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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