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ON123300

Product Specifications

CAS Number

1357470-29-1

Target

Src, CDK, c-RET, FGFR, JAK, AMPK, PDGFR

Related Pathways

PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Apoptosis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Cell Cycle/Checkpoint, Stem Cells

Purity

0.9984

Bioactivity

ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM) .

Smiles

CN1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cc1

Molecular Formula

C24H27N7O

Molecular Weight

429.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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