Oclacitinib maleate
Product Specifications
CAS Number
1640292-55-2
Target
Tyrosine Kinases, JAK
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis, Stem Cells, JAK/STAT signaling
Purity
0.9992
Bioactivity
Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members, with IC50 values ranging from 10 to 99 nM, and JAK1-dependent cytokines, with IC50 ranging from 36 to 249 nM, while not inhibiting a panel of 38 non-JAK kinases.
Smiles
OC(=O)\C=C\C(O)=O.CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1ncnc2[nH]ccc12
Molecular Formula
C15H23N5O2S·C4H4O4
Molecular Weight
453.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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