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L-685458

Product Specifications

CAS Number

292632-98-5

Target

Gamma-secretase, Apoptosis

Related Pathways

Stem Cells, Proteases/Proteasome, Neuroscience, Apoptosis

Purity

0.998

Bioactivity

L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.

Smiles

CC(C)C[C@H](NC(=O)[C@@H](C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

Molecular Formula

C39H52N4O6

Molecular Weight

672.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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