AUZ 454
Product Specifications
CAS Number
853299-07-7
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9959
Bioactivity
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd values of 50 nM for CDK2 (WT), 18.6 nM for CDK2 (C118L), 15.4 nM for CDK2 (A144C), and 9.7 nM for CDK2 (C118L/A144C) .
Smiles
CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc(N)n4)cc3)cc2C(F)(F)F)CC1
Molecular Formula
C24H26F3N7O2
Molecular Weight
501.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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