Halofuginone
Product Specifications
CAS Number
55837-20-2
Target
TGF-beta/Smad, Sodium Channel, DNA/RNA Synthesis, Calcium Channel, Parasite
Related Pathways
Microbiology/Virology, Membrane transporter/Ion channel, Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Stem Cells
Purity
0.9953
Bioactivity
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase (Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
Smiles
O[C@@H]1CCCN[C@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O
Molecular Formula
C16H17BrClN3O3
Molecular Weight
414.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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