Halofuginone

Product Specifications

CAS Number

55837-20-2

Target

TGF-beta/Smad|||Sodium Channel|||DNA/RNA Synthesis|||Calcium Channel|||Parasite

Related Pathways

Microbiology/Virology|||Membrane transporter/Ion channel|||Metabolism|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Stem Cells

Purity

0.9953

Bioactivity

Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase (Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-? signaling at 10 ng/ml in the mammal.

Smiles

O[C@@H]1CCCN[C@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O

Molecular Formula

C16H17BrClN3O3

Molecular Weight

414.68

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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