Uprosertib
Product Specifications
CAS Number
1047634-65-0
Target
Akt
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Purity
0.9973
Bioactivity
Uprosertib (GSK2141795) is a potent, selective Akt broad-spectrum inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3.
Smiles
Cn1ncc(Cl)c1-c1cc(oc1Cl)C(=O)NC(CN)Cc1ccc(F)c(F)c1
Molecular Formula
C18H16Cl2F2N4O2
Molecular Weight
429.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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