GSK-J1

Product Specifications

CAS Number

1373422-53-7

Target

Histone Demethylase

Related Pathways

Chromatin/Epigenetic

Purity

0.9967

Bioactivity

GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

Smiles

OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

Molecular Formula

C22H23N5O2

Molecular Weight

389.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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