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GDC-0623

Product Specifications

CAS Number

1168091-68-6

Target

MEK, Apoptosis

Related Pathways

Apoptosis, MAPK

Purity

0.9902

Bioactivity

GDC-0623 (RG 7421) is a potent, ATP-uncompetitive MEK1 inhibitor with a Ki of 0.13 nM, currently in Phase 1.

Smiles

OCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F

Molecular Formula

C16H14FIN4O3

Molecular Weight

456.21

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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