GDC-0623
Product Specifications
CAS Number
1168091-68-6
Target
MEK, Apoptosis
Related Pathways
Apoptosis, MAPK
Purity
0.9902
Bioactivity
GDC-0623 (RG 7421) is a potent, ATP-uncompetitive MEK1 inhibitor with a Ki of 0.13 nM, currently in Phase 1.
Smiles
OCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F
Molecular Formula
C16H14FIN4O3
Molecular Weight
456.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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