Tretazicar
Product Specifications
CAS Number
21919-05-1
Target
DNA Alkylator/Crosslinker, Reductase, DNA Alkylation
Related Pathways
Metabolism, DNA Damage/DNA Repair, Endocrinology/Hormones
Purity
0.997
Bioactivity
CB1954 (Tretazicar (NSC-115829) ), an anticancer prodrug, is activated by NAD (P) H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
Smiles
NC(=O)c1cc(N2CC2)c(cc1[N+]([O-])=O)[N+]([O-])=O
Molecular Formula
C9H8N4O5
Molecular Weight
252.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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