Bitopertin
Product Specifications
CAS Number
845614-11-1
Target
GlyT
Related Pathways
Neuroscience
Purity
>99.99%
Bioactivity
Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.
Smiles
C[C@H](Oc1ccc(cc1C(=O)N1CCN(CC1)c1ncc(cc1F)C(F)(F)F)S(C)(=O)=O)C(F)(F)F
Molecular Formula
C21H20F7N3O4S
Molecular Weight
543.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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