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Bitopertin

Product Specifications

CAS Number

845614-11-1

Target

GlyT

Related Pathways

Neuroscience

Purity

>99.99%

Bioactivity

Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.

Smiles

C[C@H](Oc1ccc(cc1C(=O)N1CCN(CC1)c1ncc(cc1F)C(F)(F)F)S(C)(=O)=O)C(F)(F)F

Molecular Formula

C21H20F7N3O4S

Molecular Weight

543.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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