A-1155463
Product Specifications
CAS Number
1235034-55-5
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
0.99
Bioactivity
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W (Ki=19 nM) and MCL-1 (Ki>440 nM) .
Smiles
C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3
Molecular Formula
C35H32FN5O4S2
Molecular Weight
669.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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