SPDP
Product Specifications
CAS Number
68181-17-9
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Purity
>99.99%
Bioactivity
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could activate equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) .
Smiles
O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O
Molecular Formula
C12H12N2O4S2
Molecular Weight
312.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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