Bafilomycin A1

Product Specifications

CAS Number

88899-55-2

Target

Autophagy|||Apoptosis|||Proton pump|||Antibiotic|||Antibacterial

Related Pathways

Microbiology/Virology|||Autophagy|||Membrane transporter/Ion channel|||Apoptosis

Purity

0.9936

Bioactivity

Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.

Smiles

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