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WAY-600

Product Specifications

CAS Number

1062159-35-6

Target

Src, mTOR, VEGFR, PI3K

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling

Purity

0.9988

Bioactivity

WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308), and is selective for mTOR over PI3Kα (>100-fold) and PI3Kγ (>500-fold) .

Smiles

C(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1

Molecular Formula

C28H30N8O

Molecular Weight

494.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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