Varlitinib
Product Specifications
CAS Number
845272-21-1
Target
EGFR, HER
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Purity
0.997
Bioactivity
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50 values of 7 nM for HER1, 2 nM for HER2, and 4 nM for HER4.
Smiles
C[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1
Molecular Formula
C22H19ClN6O2S
Molecular Weight
466.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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