Varlitinib

Product Specifications

CAS Number

845272-21-1

Target

EGFR|||HER

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Purity

0.997

Bioactivity

Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50 values of 7 nM for HER1, 2 nM for HER2, and 4 nM for HER4.

Smiles

C[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1

Molecular Formula

C22H19ClN6O2S

Molecular Weight

466.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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