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Tyrphostin AG 879

Product Specifications

CAS Number

148741-30-4

Target

PDGFR, Apoptosis, HER, EGFR, Trk receptor

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis

Purity

0.9905

Bioactivity

Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 with an IC50 of 1 μM, demonstrating 100- and 500-fold higher selectivity for ErbB2 over EGFR and PDGFR, respectively.

Smiles

CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C

Molecular Formula

C18H24N2OS

Molecular Weight

316.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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