Tyrphostin AG 879
Product Specifications
CAS Number
148741-30-4
Target
PDGFR, Apoptosis, HER, EGFR, Trk receptor
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
Purity
0.9905
Bioactivity
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 with an IC50 of 1 μM, demonstrating 100- and 500-fold higher selectivity for ErbB2 over EGFR and PDGFR, respectively.
Smiles
CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C
Molecular Formula
C18H24N2OS
Molecular Weight
316.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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