NCRW0005-F05
NCRW0005-F05 is a potent GPR139 antagonist with an IC50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesity and Parkinson's disease[1].
Product Specifications
CAS Number
[342779-66-2]
UNSPSC
12352005
Target
GPR139
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ncrw0005-f05.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1N(C2=CC=CC=C2)C(C3=CC=C(OC)C=C3)C1(F)F
Molecular Formula
C16H13F2NO2
Molecular Weight
289.28
References & Citations
[1]Wang J, et al. High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139. Acta Pharmacol Sin. 2015 Jul;36 (7) :874-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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