SKI II
Product Specifications
CAS Number
312636-16-1
Target
Apoptosis, S1P Receptor, Wnt/beta-catenin
Related Pathways
GPCR/G Protein, Stem Cells, Cytoskeletal Signaling, Apoptosis
Purity
0.9997
Bioactivity
SKI II (SphK-I2) is a highly selective and non-ATP-competitive S1P receptor inhibitor (IC50: 0.5 μM) while exhibiting no inhibitory action on other kinases including PKCα, PI3K, and ERK2.
Smiles
Oc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1
Molecular Formula
C15H11ClN2OS
Molecular Weight
302.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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