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SKI II

Product Specifications

CAS Number

312636-16-1

Target

Apoptosis, S1P Receptor, Wnt/beta-catenin

Related Pathways

GPCR/G Protein, Stem Cells, Cytoskeletal Signaling, Apoptosis

Purity

0.9997

Bioactivity

SKI II (SphK-I2) is a highly selective and non-ATP-competitive S1P receptor inhibitor (IC50: 0.5 μM) while exhibiting no inhibitory action on other kinases including PKCα, PI3K, and ERK2.

Smiles

Oc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1

Molecular Formula

C15H11ClN2OS

Molecular Weight

302.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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