Refametinib
Product Specifications
CAS Number
923032-37-5
Target
MEK
Related Pathways
MAPK
Purity
>99.99%
Bioactivity
Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM) .
Smiles
S(NC1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1OC)(=O)(=O)C3(C[C@@H](CO)O)CC3
Molecular Formula
C19H20F3IN2O5S
Molecular Weight
572.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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