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Refametinib

Product Specifications

CAS Number

923032-37-5

Target

MEK

Related Pathways

MAPK

Purity

>99.99%

Bioactivity

Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM) .

Smiles

S(NC1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1OC)(=O)(=O)C3(C[C@@H](CO)O)CC3

Molecular Formula

C19H20F3IN2O5S

Molecular Weight

572.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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