Nutlin-3b
Product Specifications
CAS Number
675576-97-3
Target
E1/E2/E3 Enzyme|||Mdm2|||MDM-2/p53
Related Pathways
Ubiquitination|||Apoptosis
Purity
0.9883
Bioactivity
Nutlin-3b ((+) -Nutlin-3) is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 ?M), 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.
Smiles
COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
Molecular Formula
C30H30Cl2N4O4
Molecular Weight
581.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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