Nutlin-3b

Product Specifications

CAS Number

675576-97-3

Target

E1/E2/E3 Enzyme|||Mdm2|||MDM-2/p53

Related Pathways

Ubiquitination|||Apoptosis

Purity

0.9883

Bioactivity

Nutlin-3b ((+) -Nutlin-3) is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 ?M), 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.

Smiles

COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1

Molecular Formula

C30H30Cl2N4O4

Molecular Weight

581.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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