SAR405838

1303607-60-4

E1/E2/E3 Enzyme, Mdm2, Apoptosis, MDM-2/p53

Apoptosis, Ubiquitination

>99.99%

MI-773 (SAR405838 (MI 773) ) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.

CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1

C29H34Cl2FN3O3

562.5

Ice Packs

-20°C